After a sabotaged experiment leaves him with super strength and unbreakable skin, Luke Cage becomes a fugitive trying to rebuild his life in modern day Harlem, New York City. But he is soon pulled out of the shadows and must fight a battle for the heart of his city – forcing him to confront a past he had tried to bury.
With tension building in the streets of Harlem thanks to ruthless club owner Cottonmouth, Luke finds it increasingly difficult to live a quiet life.
Luke is pulled deeper into the fight for his neighborhood when, as a favor to an old friend, he tries to help a kid who's in trouble with Cottonmouth.
In the aftermath of a chaotic event at a favorite Harlem hangout, Luke heeds the call to action—and hits Cottonmouth where he'll feel it most.
As he rescues a victim of Cottonmouth's vengeance, Luke remembers his earlier life and the conspiracy that led to his superhuman strength.
Cottonmouth strikes back at Luke by taking his vengeance out on the people of Harlem, while detectives Knight and Scarfe face an unexpected threat.
After Cottonmouth and Scarfe's bloody clash, Luke realizes that saving the community may turn former allies into enemies, and enemies into allies.
Mariah's political career comes under fire, and Cottonmouth picks up information that could put Luke on the run.
Mariah campaigns to turn the city and the police against Luke, and not even Misty or Claire may be able to save him.
With Luke wounded and on the run, Misty faces a soul-searching interrogation. Mariah's rise to power takes a dark turn.
Luke gets closer to the truth about Reva and her part in his fate, while Mariah wrestles with the morality of her new role. Misty hunts for Luke.
In one bold move, a friend from his past puts Luke on the defensive, Misty in dire straits, and Harlem's safety in jeopardy.
Misty digs deeper for the truth as the neighborhoods' power players throw the city into confusion.
As Luke adjusts to his growing fame and tries to shut down the flow of heroin branded with his name, someone from his past reaches out.
Luke tests out his abilities on the ballfield, Misty ruffles feathers at the precinct, and Mariah plans a reunion to boost her image.
Worried Luke is heading down a dark path, Claire pays a visit to his father. Bushmaster makes a bid for Mariah's guns.
As footage of his fight with Bushmaster goes viral, Luke struggles with the aftereffects and follows a trail of clues to Tilda's shop.
Desperate to drum up quick cash for a lawsuit, Luke weighs an offer from a superfan. Mariah invites Tilda to join the new family business.
As a wave of violence rocks Harlem, everyone races to connect the dots between Piranha, Mariah, Bushmaster and the grisly find at the clinic.
Reeling from the showdown on the bridge, Luke teams up with Misty to find Piranha. The hunt for the snitch heats up. Bushmaster reveals his endgame.
While Shades, Mariah and Misty come to terms with the previous night's events, Bushmaster searches for a way to boost his strength.
Hunkered down in a makeshift safe house, Luke and Misty butt heads over how to handle Mariah. Meanwhile, long-buried family secrets come to light.
Danny Rand insists on helping Luke hunt for Bushmaster -- the Iron Fist way. Mariah sets out to reclaim her empire. Misty pursues a traitor.
Shaken by Mariah's latest act, Luke combs the city for a witness. Flashbacks reveal a fateful encounter between the Stokes and McIver families.
Luke teams up with an unlikely ally to combat a new strain of heroin. As Shades plows ahead with his plan, a massive party draws everyone to the club.